In 2024, Ibanez introduced the RG421S, a stellar member of the RG series, proudly featured in the Standard line. The RG421S features Meranti body bolted to a one-piece maple neck with a 24-fret jatoba fingerboard with white dots position markers and black side dots . Components include a pair of Ibanez Quantum humbucking pickups, an F106 fixed bridge, Die-cast tuning machine and black hardware.
Specifications:
| Body Material | Meranti |
| Neck Profile | Wizard III |
| Fretboard Material | Jatoba |
| Fretboard Radius | 400mmR |
| Scale Length | 25.5″(648mm) |
| No. of Frets | 24 Jumbo Frets |
| Fretboard Inlays | Sharktooth Inlays |
| Pickups | Quantum Passive/Ceramic Humbucker (Bridge), Quantum Passive/Ceramic Humbucker (Neck) |
| Bridge | F106 bridge |
| Strings | D’Addario® EXL110, .010, .013, .017, .026, .036, .046 Gauges |
| Tuning Machines | Ibanez Die-Cast |
| Hardware Finish | Cosmo Black |






